| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 |
| Match list: | By round By date Latest | Player stats: | Cards All players |
| R | Date | Home | Score | Away | HT | >2.5 | HT | FT | |
| 1 | 8/25/2019 | Torino | 2 - 1 | Sassuolo | 1-0 | Yes | 1 | 1 | |
| 2 | 9/1/2019 | Sassuolo | 4 - 1 | Sampdoria | 3-0 | Yes | 1 | 1 | |
| 3 | 9/15/2019 | AS Roma | 4 - 2 | Sassuolo | 4-0 | Yes | 1 | 1 | |
| 4 | 9/22/2019 | Sassuolo | 3 - 0 | SPAL | 2-0 | Yes | 1 | 1 | |
| 5 | 9/25/2019 | Parma | 1 - 0 | Sassuolo | 0-0 | No | X | 1 | |
| 6 | 9/28/2019 | Sassuolo | 1 - 4 | Atalanta | 0-4 | Yes | 2 | 2 | |
| 8 | 10/20/2019 | Sassuolo | 3 - 4 | Inter Milan | 1-3 | Yes | 2 | 2 | |
| 9 | 10/25/2019 | Hellas Verona | 0 - 1 | Sassuolo | 0-0 | No | X | 2 | |
| 10 | 10/30/2019 | Sassuolo | 1 - 2 | Fiorentina | 1-0 | Yes | 1 | 2 | |
| 11 | 11/3/2019 | Lecce | 2 - 2 | Sassuolo | 2-1 | Yes | 1 | X | |
| 12 | 11/8/2019 | Sassuolo | 3 - 1 | Bologna | 1-0 | Yes | 1 | 1 | |
| 13 | 11/24/2019 | Sassuolo | 1 - 2 | Lazio | 1-1 | Yes | X | 2 | |
| 14 | 12/1/2019 | Juventus | 2 - 2 | Sassuolo | 1-1 | Yes | X | X | |
| 15 | 12/8/2019 | Sassuolo | 2 - 2 | Cagliari | 2-0 | Yes | 1 | X | |
| 16 | 12/15/2019 | AC Milan | 0 - 0 | Sassuolo | 0-0 | No | X | X | |
| 7 | 12/18/2019 | Brescia | 0 - 2 | Sassuolo | 0-1 | No | 2 | 2 | |
| 17 | 12/22/2019 | Sassuolo | 1 - 2 | Napoli | 1-0 | Yes | 1 | 2 | |
| 18 | 1/5/2020 | Genoa | 2 - 1 | Sassuolo | 1-1 | Yes | X | 1 | |
| 19 | 1/12/2020 | Udinese | 3 - 0 | Sassuolo | 1-0 | Yes | 1 | 1 | |
| 20 | 1/18/2020 | Sassuolo | 2 - 1 | Torino | 0-1 | Yes | 2 | 1 | |
| 21 | 1/26/2020 | Sampdoria | 0 - 0 | Sassuolo | 0-0 | No | X | X | |
| 22 | 2/1/2020 | Sassuolo | 4 - 2 | AS Roma | 3-0 | Yes | 1 | 1 | |
| 23 | 2/9/2020 | SPAL | 1 - 2 | Sassuolo | 1-0 | Yes | 1 | 2 | |
| 24 | 2/16/2020 | Sassuolo | 0 - 1 | Parma | 0-1 | No | 2 | 2 | |
| 26 | 3/9/2020 | Sassuolo | 3 - 0 | Brescia | 1-0 | Yes | 1 | 1 | |
| 25 | 6/21/2020 | Atalanta | 4 - 1 | Sassuolo | 3-0 | Yes | 1 | 1 | |
| 27 | 6/24/2020 | Inter Milan | 3 - 3 | Sassuolo | 2-1 | Yes | 1 | X | |
| 28 | 6/28/2020 | Sassuolo | 3 - 3 | Hellas Verona | 0-0 | Yes | X | X | |
| 29 | 7/1/2020 | Fiorentina | 1 - 3 | Sassuolo | 0-2 | Yes | 2 | 2 | |
| 30 | 7/4/2020 | Sassuolo | 4 - 2 | Lecce | 1-1 | Yes | X | 1 | |
| 31 | 7/8/2020 | Bologna | 1 - 2 | Sassuolo | 0-1 | Yes | 2 | 2 | |
| 32 | 7/11/2020 | Lazio | 1 - 2 | Sassuolo | 1-0 | Yes | 1 | 2 | |
| 33 | 7/15/2020 | Sassuolo | 3 - 3 | Juventus | 1-2 | Yes | 2 | X | |
| 34 | 7/18/2020 | Cagliari | 1 - 1 | Sassuolo | 0-1 | No | 2 | X | |
| 35 | 7/21/2020 | Sassuolo | 1 - 2 | AC Milan | 1-2 | Yes | 2 | 2 | |
| 36 | 7/25/2020 | Napoli | 2 - 0 | Sassuolo | 1-0 | No | 1 | 1 | |
| 37 | 7/29/2020 | Sassuolo | 5 - 0 | Genoa | 2-0 | Yes | 1 | 1 | |
| 38 | 8/2/2020 | Sassuolo | 0 - 1 | Udinese | 0-0 | No | X | 2 |